JMX0207 is a niclosamide-derived compound that demonstrates enhanced inhibitory efficacy against the NS3-NS2B protein-protein interaction essential for viral protease activity.JMX0207 effectively suppresses viral replication and protease function, showing superior antiviral activity in cell-based assays and significantly reducing Zika virus infection levels in three-dimensional mini-brain organoid models derived from pluripotent neural stem cells, thus highlighting its promise as an optimized antiviral lead compound.
Molecular Weight:
337.67
CAS Number:
[33580-97-1]
Formula:
C13H8ClN3O6
Target:
Others
T69416
T69416
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