Vestipitant, also known as GW597599, is one of the most potent and selective NK(1) receptor antagonists ever discovered, showing appropriate pharmacokinetic properties and in vivo activity. Its actions support the utility of NK(1) receptor blockade in the alleviation of anxiety and, possibly, depression. It is under development as a potential antiemetic and anxiolytic drug, and as a treatment for tinnitusand insomnia.
Molecular Weight:
491.45
CAS Number:
[334476-46-9]
Formula:
C23H24F7N3O
Target:
Others|||Neurokinin receptor
T69420
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