APBC is a novel PD-L1 inhibitor, effectively interrupting the PD-1/PD-L1 interaction by directly binding to PD-L1, presenting the KD and IC50 values at low-micromolar level, displaying superior antitumor efficacy in hPD-L1 knock-in B16F10-bearing mouse model without the induction of observable liver toxicity.
Molecular Weight:
316.35
CAS Number:
[324054-99-1]
Formula:
C20H16N2O2
Target:
Others
T69447
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