TC-5115 is a highly potent, selective inhibitor of the SET domain of the histone lysine methyltransferase MLL1 (KMT2A), with an IC50 value of 16 nM. TC-5115 exhibits weak inhibitory activity against other methyltransferases such as SET7/9, DOT1L, and EZH2 (IC50 > 1 µM). TC-5115 induces differentiation and growth arrest in leukemia cells and can be used in leukemia research.
Molecular Weight:
532.62
Purity:
99.44%
CAS Number:
[2458182-10-8]
Formula:
C23H32N8O5S
Target:
Histone Methyltransferase
T69624
* VAT and and shipping costs not included. Errors and price changes excepted
