VRT-043198, the drug metabolite of VX-765 (Belnacasan), is a potent, selective, and blood-brain barrier permeable inhibitor of the interleukin-converting enzyme/caspase-1 subfamily caspases, displaying Ki values of 0.8 nM for ICE/caspase-1 and 0.6 nM for caspase-4, respectively.
Molecular Weight:
480.94
CAS Number:
[244133-31-1]
Formula:
C22H29ClN4O6
Target:
Others|||Drug Metabolite|||Caspase
T69632
* VAT and and shipping costs not included. Errors and price changes excepted
