BAY-707 is a substrate-competitive, highly potent and selective inhibitor of MTH1. Despite superior cellular target engagement and pharmacokinetic properties, inhibition of MTH1 with BAY-707 resulted in a clear lack of in vitro or in vivo anticancer efficacy either in mono- or in combination therapies.
Molecular Weight:
348.18
CAS Number:
[2223023-19-4]
Formula:
C17H24N4O4
Target:
Others|||DNA/RNA Synthesis
T69776
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