GSK3527497 is a potent and selective inhibitor of Transient Receptor Potential Vanilloid-4 (TRPV4) with IC50 = 12 nM) for the treatment of heart failure and respiratory diseases. GSK3527497 is a preclinical candidate suitable for oral and iv administration that is projected to inhibit TRPV4 effectively in patients from a low daily clinical dose.
Molecular Weight:
463.3054
CAS Number:
[2215855-51-7]
Formula:
C17H17Cl2FN4O4S
Target:
Others
T69784
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