Ruboxistaurin mesylate monohydrate, CAS [[202260-21-7]]
Biozol Catalog Number:
TGM-T69990
Supplier Catalog Number:
T69990
Alternative Catalog Number:
TGM-T69990-25MG,TGM-T69990-50MG,TGM-T69990-100MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Ruboxistaurin mesylate monohydrate is a PKC beta inhibitor potentially for the treatment of diabetic nephropathy and diabetic macular edema. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-beta1/Smad and GRAP pathways. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt.
Molecular Weight:
582.67
CAS Number:
[202260-21-7]
Formula:
C29H34N4O7S
Target:
Others
T69990
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