Ibrexafungerp citrate is a triterpenoid antifungal agent that inhibits the synthesis of 1,3-beta-D-glucan in fungal cell walls, and although its functional outcome is similar to echinocandins, it binds to a distinct site on the glucan synthase enzyme, resulting in limited cross-resistance. Ibrexafungerp citrate exhibit concentration-dependent fungicidal activity against Candida species and retaining strong in vitro efficacy against the majority of fluconazole-resistant strains, supporting its use in antifungal resistance and drug development research.
Molecular Weight:
922.16
CAS Number:
[1965291-08-0]
Formula:
C50H75N5O11
Target:
Antifungal
T70029
T70029
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