PF-06463922 acetate is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against all known ALK and ROS1 mutants identified in patients with crizotinib-resistant disease. PF-06463922 is in clinical trials for the treatment of non-small cell lung cancer (NSCLC).
Molecular Weight:
466.46
CAS Number:
[1924207-18-0]
Formula:
C23H23FN6O4
Target:
ALK|||Apoptosis|||ROS Kinase|||Others
T70060
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