LFS-829, CAS [[1799330-89-4]]

Catalog Number: TGM-T70180
Article Name: LFS-829, CAS [[1799330-89-4]]
Biozol Catalog Number: TGM-T70180
Supplier Catalog Number: T70180
Alternative Catalog Number: TGM-T70180-25MG,TGM-T70180-50MG,TGM-T70180-100MG
Manufacturer: TargetMol
Category: Biochemikalien
LFS-829 is a a small-molecule antagonist of exportin-1. LFS-829 showed low-range nanomolar activities. Oral administration of LFS-829 can significantly reverse the pathological features of colitis model mice. LFS-829 can attenuate dual NF-kappaB signaling and the Nrf2 cytoprotection pathway via targeting exportin-1 in colitis mice. Moreover, LFS-829 has a very low risk of cardiotoxicity and acute toxicity. LFS-829 holds great promise for the treatment of colitis and may warrant translation for use in clinical trials.
Molecular Weight: 373.34
CAS Number: [1799330-89-4]
Formula: C13H9F6NOS2
Target: Others
T70180