DRVYIHPF , Angiotensin II , Hypertensin II , Ang II
Angiotensin II is a major biologically active vasoconstrictor peptide that regulates blood pressure by binding to AT1R and AT2R receptors. It stimulates the sympathetic nervous system, promotes aldosterone synthesis, and enhances renal function. Additionally, it induces vascular smooth muscle cell proliferation and increases collagen synthesis, leading to vascular and myocardial hypertrophy and fibrosis. It also promotes apoptosis and endothelial capillary formation. Angiotensin II is commonly used to induce hypertension and cardiac hypertrophy animal models.
Molecular Weight:
1046.18
Purity:
>99.99%
CAS Number:
[4474-91-3]
Formula:
C50H71N13O12
Target:
Apoptosis|||RAAS
T7040
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