TAK-448 is an investigational oligopeptide analog of kisspeptin and a potent agonist of the GPR54 receptor. In animals, acute TAK-448 administration stimulates LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. TAK-448 has exhibited potent antitumor activity in rat androgen-dependent prostate cancer models. Therefore, TAK-448 may be useful in the treatment of PC in humans..
Molecular Weight:
1339.4
CAS Number:
[1433222-47-9]
Formula:
C60H81F3N16O16
Target:
Others
T70670
* VAT and and shipping costs not included. Errors and price changes excepted
