ent-Abacavir is an enatiomer of Abacavir. Abacavir is a carbocyclic 2-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Molecular Weight:
286.33
CAS Number:
[136470-79-6]
Formula:
C14H18N6O
Target:
Others
T70859
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