K811 is an ASK1-specific inhibitor that prolongs survival in a mouse model of amyotrophic lateral sclerosis. K811 efficiently prevented cell proliferation in cell lines with high ASK1 expression and in HER2-overexpressing GC cells. Treatment with K811 reduced sizes of xenograft tumors by downregulating proliferation markers.
Molecular Weight:
510.54
CAS Number:
[1355228-38-4]
Formula:
C29H26N4O5
Target:
Others
T70893
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