GBR-12935 is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinsons disease, although selective radioligands such as Ioflupane (AAAI) are now available for this application. GBR-12935 is now widely used in animal research into Parkinsons disease and the dopamine pathways in the brain. (Source: http://en.wikipedia.org/wiki/GBR-12935).
Molecular Weight:
530.665
CAS Number:
[1349767-56-1]
Formula:
C32H38N2O5
Target:
Others|||Dopamine Receptor
T70914
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