The immunoregulator spleen tyrosine kinase (SYK) is upregulated in cutaneous lupus erythematosus (CLE). This double-blind, multicentre, Phase Ib study evaluated the safety, tolerability, pharmacokinetics, pharmacodynamics and clinical efficacy of the selective SYK inhibitor GSK2646264 in active CLE lesions
Molecular Weight:
382.48
CAS Number:
[1345461-77-9]
Formula:
C21H27FN6
Target:
Others
* VAT and and shipping costs not included. Errors and price changes excepted