AM-9635 is a potent and selective PI3Kdelta inhibitor. AM-9635 showes good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-96352 inhibits KLH-specific IgG and IgM in a dosedependent manner AM-9635 is well tolerated at all doses and exhibits significantly reduced IgG and IgM specific antibodies . PI3Kalpha and PI3Kbeta are ubiquitously expressed and play a role in cell growth, division, and survival.
Molecular Weight:
392.36
CAS Number:
[1338483-10-5]
Formula:
C19H14F2N8
Target:
Others|||PI3K|||Akt
T70943
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