Maprotiline-d3 hydrochloride, CAS [[1329496-63-0]]

Product Overview

• Article Name: Maprotiline-d3 hydrochloride, CAS [[1329496-63-0]]
• Biozol Catalog Number: TGM-T70960
• Supplier Catalog Number: T70960
• Alternative Catalog Number: TGM-T70960-1MG,TGM-T70960-5MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

Maprotiline-d3 is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selective for NET over the serotonin and dopamine transporters. Maprotiline also binds to the serotonin (5-HT) receptor subtype 5-HT2A, as well as histamine H1, muscarinic acetylcholine, alpha1-adrenergic, and dopamine D2 receptors. In vivo, maprotiline inhibits norepinephrine reuptake in rat brain and peripheral tissues. It reduces isolation-induced aggressive behavior and inhibits electrical foot-shock stimulation-induced belligerence in mice when administered at doses ranging from 3 to 10 mg/kg. Maprotiline also reduces aggressive behavior in rhesus monkeys housed in groups. Formulations containing maprotiline have been used in the treatment of depression and anxiety.

Product Properties

• Molecular Weight: 316.8873
• CAS Number: [1329496-63-0]
• Formula: C20H21D3ClN
• Target: Autophagy

Images

T70960