PLX5622 is an orally active small-molecule CSF1R inhibitor that selectively depletes microglia in the brains of mice and rats. It is commonly used to establish models related to microglia-associated neuroinflammation, neurodegenerative diseases (such as Alzheimers disease and Parkinsons disease), brain injury, and neuroimmune regulation. This product is also available as a premixed diet version (C2005 PLX5622 in AIN-76A Diet (1200 ppm)), eliminating the need for self-preparation and offering superior stability and reproducibility.
Molecular Weight:
395.41
Purity:
99.97%
CAS Number:
[1303420-67-8]
Formula:
C21H19F2N5O
Target:
CSF-1R|||c-Fms
T7100
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