Famitinib malate (SHR1020) is an orally active multi-targeted kinase inhibitor that effectively inhibits the activity of c-kit, VEGFR-2, and PDGFRbeta with IC50 values of 2.3 nM, 4.7 nM, and 6.6 nM, respectively. It induces cell apoptosis and demonstrates potent antitumor activity in human gastric cancer cells and xenografts, making it a valuable compound for cancer research.
Molecular Weight:
544.57
CAS Number:
[1256377-67-9]
Formula:
C27H33FN4O7
Target:
Others|||PDGFR|||Apoptosis|||VEGFR
T71111
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