Poloxipan is a potent and pan-specific PLK1 inhibitor. In vitro, Poloxipan has IC50 3.2 uM (Plk1), 1.7 uM (Plk2), and 3 uM (Plk3). Poloxipan showed minor inhibition over FHA dommain of Chk2, S2 domian of STAT1, STAT5b, Lck, etc.
Molecular Weight:
380.22
CAS Number:
[1239513-63-3]
Formula:
C14H10BrN3O3S
Target:
Others|||STAT|||PLK
T71156
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