Foretinib phosphate is an orally bioavailable small molecule with potential antineoplastic activity. MET/VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of tumor angiogenesis, tumor cell proliferation and metastasis. The proto-oncogene c-MET has been found to be over-expressed in a variety of cancers.
Molecular Weight:
828.65
CAS Number:
[1226999-07-0]
Formula:
C34H40F2N4O14P2
Target:
VEGFR|||c-Met/HGFR|||Others
T71187
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