AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.
Molecular Weight:
535.56
Purity:
98.06%
CAS Number:
[882663-88-9]
Formula:
C29H28F3N5O2
Target:
Ras|||Kras|||VEGFR|||p38 MAPK|||JAK|||Src
T7123
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