LEQ506, also known as NPV-LEQ506, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Smoothened antagonist LEQ506 selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway, thereby inhibiting tumor cell growth.
Molecular Weight:
439.55
CAS Number:
[1057677-92-5]
Formula:
C27H29N5O
Target:
Hedgehog/Smoothened|||Others
T71520
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