Enzastaurin HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin HCl selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.
Molecular Weight:
552.08
CAS Number:
[359017-79-1]
Formula:
C32H30ClN5O2
Target:
Others|||PKC|||Autophagy|||Apoptosis
T71853
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