Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers form symmetric synaptic connections with motoneurons innervating skeletal muscles of the lower limbs in lamina IX of the spinal ventral horn and EM-2 might exert inhibitory effects on the activities of these motoneurons through both presynaptic and postsynaptic mechanisms.
Molecular Weight:
571.67
Purity:
95%
CAS Number:
[141801-26-5]
Formula:
C32H37N5O5
Target:
Opioid Receptor
T7218
* VAT and and shipping costs not included. Errors and price changes excepted
