Ladostigil hydrochloride (TV-3326), an orally active compound, acts as a dual inhibitor targeting both cholinesterase and brain-selective monoamine oxidase (MAO), demonstrating inhibition constants (IC50s) of 31.8 µM for acetylcholinesterase (AChE) and 37.1 µM for MAO-B. This compound exhibits neuroprotective, antioxidant, and anti-inflammatory properties, making it useful for research into depression and Alzheimers disease.
Molecular Weight:
308.8
CAS Number:
[209394-18-3]
Formula:
C16H21ClN2O2
Target:
Others|||Monoamine Oxidase|||Cholinesterase (ChE)
T72247
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