TAK-960 dihydrochloride is an orally administered, selective polo-like kinase 1 (PLK1) inhibitor with a potent IC50 of 0.8 nM. It also targets PLK2 and PLK3 with IC50 values of 16.9 and 50.2 nM, respectively. This compound effectively inhibits the proliferation of a broad range of cancer cell lines and demonstrates substantial efficacy against various tumor xenografts.
Molecular Weight:
634.52
Formula:
C27H36Cl2F3N7O3
Target:
Others|||PLK
T72269
* VAT and and shipping costs not included. Errors and price changes excepted
