WYE-687 dihydrochloride is an ATP-competitive inhibitor of mTOR, demonstrating potent activity with an IC50 value of 7 nM. It effectively suppresses the activation of both mTORC1 and mTORC2. Additionally, WYE-687 exhibits inhibitory effects on PI3Kalpha and PI3Kgamma, with IC50 values of 81 nM and 3.11 µM, respectively.
Molecular Weight:
601.53
CAS Number:
[1702364-87-1]
Formula:
C28H34Cl2N8O3
Target:
mTOR|||Others|||PI3K
T72270
* VAT and and shipping costs not included. Errors and price changes excepted