Bleximenib (JNJ-75276617) oxalate is an orally active and highly selective menin-KMT2A interaction inhibitor, with IC50 values of 0.1 nM in humans, 0.045 nM in mice, and 0.066 nM in dogs, Bleximenib effectively suppresses tumor cell proliferation while inducing apoptosis and cellular differentiation. Bleximenib serves as a powerful investigational agent for leukemia and other KMT2A-driven malignancies in preclinical cancer research.
Molecular Weight:
599.8
CAS Number:
[2654081-35-1]
Formula:
C32H50FN7O3
Target:
Histone Methyltransferase
T72359
* VAT and and shipping costs not included. Errors and price changes excepted
