Lapatinib tosylate (GW572016), a robust and orally administered inhibitor specifically targeting the tyrosine kinase domains of ErbB-2 and EGFR, exhibits inhibitory concentration 50 (IC50) values of 10.2 nM and 9.8 nM against purified EGFR and ErbB-2, respectively.
Molecular Weight:
753.26
CAS Number:
[1187538-35-7]
Formula:
C36H34ClFN4O7S2
Target:
EGFR|||Autophagy|||Ferroptosis|||Others
T72577
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