TTK inhibitor 3 (compound 25) is a selective inhibitor of TTK (Threonine Tyrosine Kinase) with an IC50 of 3.0 nM for TTK and 16.0 nM for CAL-51 cells. It inhibits tumor growth in CAL-51 xenograft models and TNBC (triple-negative breast cancer) PDX models.
Molecular Weight:
727.9
Purity:
0.9944
CAS Number:
[2820453-41-4]
Formula:
C42H49N9O3
Target:
Tyrosine Kinases
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