RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 µM and 31.09 nM, respectively. It demonstrates significant neuroprotective effects against Abeta25-35-induced neuronal damage and alleviates depressive behavior in mice. RAGE/SERT-IN-1 is useful for research on the comorbidity of Alzheimers disease and depression [1].
Molecular Weight:
637.28
CAS Number:
[2766739-35-7]
Formula:
C38H41ClN4OS
Target:
Others|||Beta Amyloid|||Serotonin Transporter
T72824
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