SHP2/HDAC-IN-1, a dual allosteric inhibitor targeting SHP2 and HDAC, exhibits potent inhibitory effects with IC 50 values of 20.4 nM (SHP2) and 25.3 nM (HDAC1), respectively. This compound activates T cells, enhances antigen presentation, and promotes cytokine secretion, facilitating efficient antitumor immunity. It holds potential for cancer immunotherapy research.
Molecular Weight:
660.59
CAS Number:
[2831230-38-5]
Formula:
C34H35Cl2N7O3
Target:
Phosphatase|||Others|||HDAC
T72839
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