VEGFR-3-IN-1 is a novel, potent, and selective VEGFR3 inhibitor with an IC50 of 110.4 nM. It exhibits antitumor activity, inactivates the VEGFR3 signaling pathway, and inhibits the proliferation and migration of VEGF-C-induced human dermal lymphatic endothelial cells (HDLEC), MDA-MB-231, and MDA-MB-436 cells.
Molecular Weight:
616.1
Purity:
99.95%
CAS Number:
[2756668-73-0]
Formula:
C29H29ClF3N7OS
Target:
VEGFR
T72924
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