CDK4/6-IN-14 is a potent, highly selective inhibitor of Cyclin-Dependent Kinases 4 and 6 (CDK4/6), with inhibition concentrations (IC50s) of 10 nM and 16 nM, respectively. It shows over 60-fold selectivity for CDK4/6 compared to CDKs 1, 2, 7, and 9, and exhibits significant selectivity against 205 other kinases.
Molecular Weight:
483.97
CAS Number:
[2699091-15-9]
Formula:
C24H27ClFN7O
Target:
Others|||CDK
T72951
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