Compound 13h (hGGPPS-IN-3) is a potent inhibitor of human geranylgeranyl pyrophosphate synthase (hGGPPS), characterized as a C-2-substituted thienopyrimidine-based bisphosphonate analogue (C2-ThP-BPs). It selectively induces apoptosis in multiple myeloma (MM) cells and demonstrates antimyeloma activity in vivo [1].
Molecular Weight:
613.31
CAS Number:
[2763223-96-5]
Formula:
C21H19BrN4O7P2S
Target:
Apoptosis
T72989
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