c-Met-IN-14, a N-sulfonylamidine-based derivative, is a selective c-Met kinase inhibitor with an IC50 value of 2.89 nM. It exhibits anticancer properties by inhibiting c-Met phosphorylation and arresting the cell cycle at the G2/M phase. Additionally, c-Met-IN-14 promotes dose-dependent apoptosis in A549 cells.
Molecular Weight:
701.2
CAS Number:
[2443380-34-3]
Formula:
C34H38ClFN4O7S
Target:
FLT|||Apoptosis|||c-Kit|||c-Met/HGFR|||Others
T73022
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