RGB-286638, CAS [[784210-87-3]]
Catalog Number:
TGM-T73196
| Article Name: |
RGB-286638, CAS [[784210-87-3]] |
| Biozol Catalog Number: |
TGM-T73196 |
| Supplier Catalog Number: |
T73196 |
| Alternative Catalog Number: |
TGM-T73196-25MG,TGM-T73196-50MG,TGM-T73196-100MG |
| Manufacturer: |
TargetMol |
| Category: |
Biochemikalien |
| RGB-286638 is a multi-target CDK inhibitor that effectively hampers the kinase activity of a range of cyclin-CDK complexes, including cyclin T1-CDK9 (IC50 = 1 nM), cyclin B1-CDK1 (IC50 = 2 nM), cyclin E-CDK2 (IC50 = 3 nM), cyclin D1-CDK4 (IC50 = 4 nM), cyclin E-CDK3 (IC50 = 5 nM), and p35-CDK5 (IC50 = 5 nM). Additionally, it inhibits other kinases such as GSK-3beta (IC50 = 3 nM), TAK1 (IC50 = 5 nM), Jak2 (IC50 = 50 nM), and MEK1 (IC50 = 54 nM), showcasing its versatile inhibitory potential. |
| Molecular Weight: |
618.55 |
| CAS Number: |
[784210-87-3] |
| Formula: |
C29H37Cl2N7O4 |
| Target: |
Others|||MEK|||CDK|||JAK|||GSK-3 |
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|
T73196 |
