UT-B-IN-1 (UTBINH-14) is a reversible, competitive, and selective inhibitor of the urea transporter-B (UT-B) with IC50 values of 10 nM and 25 nM for human and mouse UT-B, respectively. It exhibits low toxicity and superior selectivity against UT-B compared to UT-A isoforms, enhances urine production, and decreases urine concentration in mice, making it suitable for research on diuretic mechanisms.
Molecular Weight:
455.58
CAS Number:
[892742-76-6]
Formula:
C20H17N5O2S3
Target:
Others|||Urea Transporter
T73230
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