DHFR-IN-5, an orally active and potent inhibitor of dihydrofolate reductase (DHFR), exhibits a K_i value of 0.54 nM against the quadruple mutant Plasmodium falciparum DHFR, demonstrating anti-malarial activity.
Molecular Weight:
360.41
CAS Number:
[1142407-81-5]
Formula:
C18H24N4O4
Target:
DHFR|||Others
T73328
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