EDP-305, an orally active, potent, and selective agonist of the farnesoid X receptor (FXR), exhibits EC50 values of 34 nM in chimeric FXR within CHO cells and 8 nM in full-length FXR in HEK cells. Demonstrating a potent and consistent antifibrotic effect, EDP-305 is utilized in research related to primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH).
Molecular Weight:
630.92
CAS Number:
[1933507-63-1]
Formula:
C36H58N2O5S
Target:
Phosphatase|||FXR|||Cytochromes P450|||Others
T73414
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