CFT8634 is an orally active and selective degrader targeting BRD9, with effects on the proliferation of SMARCB1-deficient cancer cell lines. CFT8634 induces the formation of a ternary complex with BRD9 and E3 ligase, inducing BRD9 ubiquitination and subsequent degradation by the proteasome.
Molecular Weight:
710.79
Purity:
99.95%
CAS Number:
[2704617-96-7]
Formula:
C37H45F3N6O5
Target:
Epigenetic Reader Domain|||PROTACs
T73425
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