FX-909 is a covalent peroxisome proliferator-activated receptor gamma (PPARgamma) inverse agonist developed for advanced solid malignancies, including muscle-invasive bladder cancer, and functional profiling and NMR studies demonstrate that FX-909 exhibits enhanced corepressor-selective inverse agonism and superior stabilization of a transcriptionally repressive PPARgamma ligand-binding domain conformation compared with T0070907.
Molecular Weight:
360.33
Purity:
99.53%
CAS Number:
[2924573-90-8]
Formula:
C17H10F2N2O3S
Target:
PPAR
T73519
T73519
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