PROTAC Bcl-xL degrader-1 is a potent PROTAC composed of a Bcl-xL (Bcl-2 family member) ligand-binding group, a linker, and an IAP E3 ligases binding group, demonstrating effectiveness as a Bcl-xL degrader. It exhibits toxicity towards human platelets and MyLa 1929 cells, with IC50 values of 62 nM and 8.5 µM, respectively [1].
Molecular Weight:
1514.28
Formula:
C76H96ClF3N10O11S3
Target:
Others|||Bcl-2 Family|||PROTACs
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