PROTAC-O4I2, a PROTAC ligand targeting splicing factor 3B1 (SF3B1), induced FLAG-SF3B1 degradation in K562 cells with an IC50 value of 0.244 µM. PROTAC-O4I2 induced apoptosis in K562 WT cells.
Molecular Weight:
609.1
Purity:
96.31%
CAS Number:
[2785323-62-6]
Formula:
C29H29ClN6O5S
Target:
PROTACs|||Apoptosis
T74186
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