(S)-V-0219 hydrochloride, an enantiomer of V-0219, serves as an orally active positive allosteric modulator (PAM) of the GLP-1 Receptor (GLP-1R), enhancing calcium fluxes in HEK cells that stably express hGLP-1R. Additionally, it effectively reduces high glucose levels and suppresses feeding behavior in fasted mice [1].
Molecular Weight:
446.89
Formula:
C20H26ClF3N4O2
Target:
Glucagon Receptor|||Others
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