PROTAC AR-V7 degrader-1, CAS [[2767440-24-2]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC AR-V7 degrader-1, CAS [[2767440-24-2]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T74410
• Supplier Catalog Number: T74410
• Alternative Catalog Number: TGM-T74410-5MG,TGM-T74410-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

PROTAC AR-V7 degrader-1 (Compound 6) is an orally bioavailable, potent, and selective degrader targeting the androgen receptor (AR) variant V7, achieving degradation with a DC50 of 0.32 µM by directing the VHL E3 ligase to the AR DNA-binding domain (DBD). It demonstrates efficacy in the 22Rv1 cell line expressing AR-V7, with an EC50 of 0.88 µM [1].

Product Properties

• Molecular Weight: 789.02
• CAS Number: [2767440-24-2]
• Formula: C41H52N6O6S2
• Target: PROTACs|||Androgen Receptor

Images

T74410