EGFR-IN-43 (Compound 17c) is a highly effective EGFR inhibitor with single-digit nanomolar activity, uniquely combining tamoxifen or endoxifen with the EGFR inhibitor gefitinib through a covalent bond, maintaining both ER antagonist activity and EGFR inhibition capabilities, demonstrating exceptional anti-cancer efficacy [1].
Molecular Weight:
860.45
Formula:
C50H55ClFN5O5
Target:
Others|||EGFR
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